Prostaglandin A1 inhibits replication of classical swine fever virus.
Mem Inst Oswaldo Cruz
; 93(6): 815-8, 1998.
Article
en En
| MEDLINE
| ID: mdl-9921308
Prostaglandins (Pgs) have been shown to inhibit the replication of several DNA and RNA viruses. Here we report the effect of prostaglandin (PgA1) on the multiplication of a positive strand RNA virus, Classical Swine Fever Virus (CSFV) in PK15 cells. PgA1 was found to inhibit the multiplication of CSFV. At a concentration of 5 micrograms/ml, which was nontoxic to the cells, PgA1 inhibitis virus production in 99%. In PgA1 treated cells the size and number of characteristic Classical Swine Fever focus decreased in amount.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prostaglandinas A
/
Replicación Viral
/
Peste Porcina Clásica
/
Virus de la Fiebre Porcina Clásica
Límite:
Animals
Idioma:
En
Revista:
Mem Inst Oswaldo Cruz
Año:
1998
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil