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Using TNM staging to predict survival in patients with squamous cell carcinoma of head & neck.
Hall, S F; Groome, P A; Rothwell, D; Dixon, P F.
Afiliación
  • Hall SF; Department of Otolaryngology, Queen's University, Kingston, Ontario, Canada.
Head Neck ; 21(1): 30-8, 1999 Jan.
Article en En | MEDLINE | ID: mdl-9890348
BACKGROUND: There is a need for a classification system for prognosis based on the TNM system for patients with squamous cell carcinoma of the head and neck such that patient groupings are homogeneous within and heterogeneous between. METHODS: Six hundred fifty-five consecutive patients with invasive squamous cell carcinoma of the head and neck followed prospectively are split into a training set and a test set. Using the training set, the Cox Proportional Hazards Model and the outcome of dead with disease, we created homogeneous prognostic levels (PLs) based on RR. Using the test set, we compare our model to others in the literature. RESULTS: Using the training set, we identified five PLs, and using the test set, we demonstrated that our model is superior to others for both within-group homogeneity and between-group heterogeneity. CONCLUSIONS: A simple classification system can be used to group patients for survival and is valid for future study in prognostication.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 1999 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 1999 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos