Evaluation of phospholipase activity of Candida albicans and its correlation with pathogenicity in mice.

Kothavade, R J; Panthaki, M H

Kothavade, R J; Panthaki, M H.

Afiliación

Kothavade RJ; Department of Dermatology, Sir J. J. Group of Hospitals and Grant Medical College, Bombay, India.

J Med Microbiol ; 47(2): 99-102, 1998 Feb.

Article en En | MEDLINE | ID: mdl-9879950

RESUMEN

Sixty-one isolates of Candida albicans were tested for their phospholipase activity and this parameter was correlated with pathogenicity in albino mice. Of the isolates tested, 57 (93%) showed appreciable phospholipase activity and of these, 55 (90%) were pathogenic to mice. A significant correlation was found between phospholipase activity and involvement of kidneys in animal pathogenicity studies. The isolates of C. albicans, that exhibited higher phospholipase activity were found to be pathogenic for mice.

Asunto(s)

Candida albicans/enzimología; Candida albicans/patogenicidad; Candidiasis/microbiología; Fosfolipasas/metabolismo; Animales; Candida albicans/aislamiento & purificación; Humanos; Riñón/microbiología; Ratones

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfolipasas / Candida albicans / Candidiasis Límite: Animals / Humans Idioma: En Revista: J Med Microbiol Año: 1998 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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