Growth inhibitory activities of kalopanaxsaponins A and I against human pathogenic fungi.

Kim, D W; Bang, K H; Rhee, Y H; Lee, K T; Park, H J

Kim, D W; Bang, K H; Rhee, Y H; Lee, K T; Park, H J.

Afiliación

Kim DW; Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University, Japan.

Arch Pharm Res ; 21(6): 688-91, 1998 Dec.

Article en En | MEDLINE | ID: mdl-9868538

RESUMEN

Antifungal activities of the compounds isolated from Kalopanax pictus against representative fungi of dermatomycosis were investigated using paper disc diffusion method. It was found that kalopanaxsaponins A and I were effective in inhibiting the growth of Candida albicans KCTC 1940 and Cryptococcus neoformans KCTC 7224 with minimum inhibitory concentration (MIC) of 25 micrograms/ml. It showed that antifungal activity of both compounds have strong selectivity against the fungi of dermatomycosis.

Asunto(s)

Antifúngicos/farmacología; Hongos/efectos de los fármacos; Hongos/crecimiento & desarrollo; Ácido Oleanólico/análogos & derivados; Saponinas/farmacología; Arthrodermataceae/efectos de los fármacos; Candida albicans/efectos de los fármacos; Cryptococcus neoformans/efectos de los fármacos; Humanos; Pruebas de Sensibilidad Microbiana; Saponinas/química

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Oleanólico / Saponinas / Hongos / Antifúngicos Límite: Humans Idioma: En Revista: Arch Pharm Res Año: 1998 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Corea del Sur

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links