Loss of motor units in Alzheimer's disease.
Electromyogr Clin Neurophysiol
; 38(8): 475-9, 1998 Dec.
Article
en En
| MEDLINE
| ID: mdl-9842482
Little attention has been paid in the literature to the state of the peripheral nervous system (PNS) in Alzheimer's disease (AD). We conducted a comprehensive electrophysiological study in 15 AD patients looking for functional abnormalities within their PNSs. A reduction of the number of functioning motor units (MU) was found in the thenar and soleus muscles of most of these patients without enlargement of the remaining MUs territories, while the motor and sensory conduction velocities of the peripheral nerves were preserved. These results suggest dysfunction of the spinal motoneurones in patients afflicted with this condition.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sistema Nervioso Periférico
/
Músculo Esquelético
/
Enfermedad de Alzheimer
/
Neuronas Motoras
/
Conducción Nerviosa
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Electromyogr Clin Neurophysiol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Bélgica