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Declining seroprevalence in a very large HIV epidemic: injecting drug users in New York City, 1991 to 1996.
Des Jarlais, D C; Perlis, T; Friedman, S R; Deren, S; Chapman, T; Sotheran, J L; Tortu, S; Beardsley, M; Paone, D; Torian, L V; Beatrice, S T; DeBernardo, E; Monterroso, E; Marmor, M.
Afiliación
  • Des Jarlais DC; Chemical Dependency Institute, Beth Israel Medical Center, New York, NY 10003, USA. dcdesjarla@aol.com
Am J Public Health ; 88(12): 1801-6, 1998 Dec.
Article en En | MEDLINE | ID: mdl-9842377
OBJECTIVES: This study assessed recent trends in HIV seroprevalence among injecting drug users in New York City. METHODS: We analyzed temporal trends in HIV seroprevalence from 1991 through 1996 in 5 studies of injecting drug users recruited from a detoxification program, a methadone maintenance program, research storefronts in the Lower East Side and Harlem areas, and a citywide network of sexually transmitted disease clinics. A total of 11,334 serum samples were tested. RESULTS: From 1991 through 1996, HIV seroprevalence declined substantially among subjects in all 5 studies: from 53% to 36% in the detoxification program, from 45% to 29% in the methadone program, from 44% to 22% at the Lower East Side storefront, from 48% to 21% at the Harlem storefront, and from 30% to 21% in the sexually transmitted disease clinics (all P < .002 by chi 2 tests for trend). CONCLUSIONS: The reductions in HIV seroprevalence seen among injecting drug users in New York City from 1991 through 1996 indicate a new phase in this large HIV epidemic. Potential explanatory factors include the loss of HIV-seropositive individuals through disability and death and lower rates of risk behavior leading to low HIV incidence.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Seroprevalencia de VIH / Abuso de Sustancias por Vía Intravenosa / Salud Urbana Tipo de estudio: Etiology_studies / Risk_factors_studies / Screening_studies Límite: Adult / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Am J Public Health Año: 1998 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Seroprevalencia de VIH / Abuso de Sustancias por Vía Intravenosa / Salud Urbana Tipo de estudio: Etiology_studies / Risk_factors_studies / Screening_studies Límite: Adult / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Am J Public Health Año: 1998 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos