Cellulose, cellulases and cellulosomes.

Bayer, E A; Chanzy, H; Lamed, R; Shoham, Y

Bayer, E A; Chanzy, H; Lamed, R; Shoham, Y.

Afiliación

Bayer EA; Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel. bfbayer@wiccmail.weizmann.ac.il

Curr Opin Struct Biol ; 8(5): 548-57, 1998 Oct.

Article en En | MEDLINE | ID: mdl-9818257

RESUMEN

The structural complexity and rigidity of cellulosic substrates have given rise to a phenomenal diversity of degradative enzymes--the cellulases. Cellulolytic microorganisms produce a wide variety of different catalytic and noncatalytic enzyme modules, which form the cellulases and act synergistically on their substrate. In some microbes, several types of cellulases are organized into an elaborate multifunctional supramolecular complex, known as the cellulosome. A combination of molecular genetic, biochemical, chemical, crystallographic and microscopic techniques are paving the way for new insights into both the structure of cellulose and the mechanisms of its hydrolysis.

Asunto(s)

Celulasa/química; Celulasa/metabolismo; Celulosa/química; Celulosa/metabolismo; Complejos Multienzimáticos/metabolismo; Bacterias/metabolismo; Conformación de Carbohidratos; Hongos/metabolismo; Modelos Moleculares; Complejos Multienzimáticos/química

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Celulasa / Celulosa / Complejos Multienzimáticos Idioma: En Revista: Curr Opin Struct Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 1998 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Reino Unido

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