[The value of DNA flow cytometry in evaluation of proliferating activity of neoplasm cells in patients with laryngeal cancer]. / Wartosc cytometrii przeplywowej DNA w ocenie zdolnosci proliferacyjnej komórek nowotworowych u chorych na raka krtani.
Otolaryngol Pol
; 52(4): 411-7, 1998.
Article
en Pl
| MEDLINE
| ID: mdl-9814024
A study of DNA ploidy was carried out including 84 cases of laryngeal squamous cell carcinoma. Material was fixed during 30 min in 3% paraformaldehyde and embedded in low-melting-point paraffin. The histologic studies were done for diagnosis and general view. Results were as follows. The highest percentage of cancers with DNA diploidy was found in well- and medium-differentiated tumors. Among well-differentiated carcinomas there were 18% diploid versus 5% polyploid tumors. In the medium-differentiated cancers there were 23.5% diploid, 6% polyploid, and 6% hyperdiploid tumors. The highest percentage of DNA hyperdiploidy and poliploido-aneuploidy was found in low-differentiated cancers. Additionally, tumor proliferative activity was evaluated in relation to the percentage of cells in phase S of cellular cycle. Special attention was paid to tumors which revealed the phenomenon of DNA poliploidy-aneuploidy beside DNA diploidy.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ploidias
/
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
/
Citometría de Flujo
Límite:
Humans
Idioma:
Pl
Revista:
Otolaryngol Pol
Año:
1998
Tipo del documento:
Article
Pais de publicación:
Polonia