Cardiovascular safety of oral contraceptives. What has changed in the last decade?
Contraception
; 58(3 Suppl): 9S-13S; quiz 65S, 1998 Sep.
Article
en En
| MEDLINE
| ID: mdl-9807687
PIP: As a result of careful patient selection, the cardiovascular safety of oral contraceptives (OCs) has improved dramatically in the past decade. The incidence of stroke and myocardial infarction is exceedingly low among women who use OCs containing 35 mcg or less of ethinyl estradiol, and formulations containing under 50 mcg of estrogen account for almost all current use in the US. This article reviews the epidemiologic data on use of OCs of varying steroid dosages on the risks of myocardial infarction, hemorrhagic and ischemic stroke, and venous thromboembolism. Although four studies published since 1995 have suggested that OCs containing desogestrel or gestodene increase the risk of venous thromboembolism above that associated with levonorgestrel, these findings are likely due to prescribing bias and differences in the duration of use. The greatest risk of an arterial cardiovascular event comes from smoking while taking OCs.^ieng
Palabras clave
Biology; Cerebrovascular Effects; Contraception; Contraceptive Methods--administraction and dosage; Contraceptive Methods--side effects; Diseases; Embolism; Family Planning; Health; Heart Diseases; Ischemia; Myocardial Infarction; Oral Contraceptives, Combined--administraction and dosage; Oral Contraceptives, Combined--side effects; Oral Contraceptives--administraction and dosage; Oral Contraceptives--side effects; Physiology; Public Health; Risk Factors; Safety; Thromboembolism; Vascular Diseases
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Anticonceptivos Orales
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Contraception
Año:
1998
Tipo del documento:
Article
Pais de publicación:
Estados Unidos