Comparison of FPLC with cellulose acetate electrophoresis for the diagnosis of beta-thalassaemia trait.
Indian J Med Res
; 108: 145-8, 1998 Oct.
Article
en En
| MEDLINE
| ID: mdl-9805844
Different electrophoretic and chromatographic techniques are described in the literature for the estimation of HbA2 levels. We compared the fast protein liquid chromatography (FPLC) technique with the conventional cellulose acetate electrophoresis (CAE) used routinely in most laboratories. Ninety five individuals from high risk groups were screened for beta-thalassaemia trait by both the techniques. The cut-off value for the diagnosis of beta-thalassaemia trait by both the techniques was 3.8 per cent and 27 heterozygotes were identified. As both techniques gave comparable results, CAE could be the cost effective method of choice for routine screening for beta-thalassaemia trait.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hemoglobina A2
/
Talasemia beta
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Indian J Med Res
Año:
1998
Tipo del documento:
Article
Pais de publicación:
India