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Antigenic and genomic diversity of central European respiratory syncytial virus strains.
Lukic-Grlic, A; Cane, P A; Bace, A; Pringle, C R; Mlinaric-Galinovic, G; Popow-Kraupp, T.
Afiliación
  • Lukic-Grlic A; Department of Microbiology, A. Stampar School of Public Health, Medical School, University of Zagreb, Croatia.
Arch Virol ; 143(7): 1441-7, 1998.
Article en En | MEDLINE | ID: mdl-9722887
Thirty-two RSV strains recovered during the winter months of 1987/88 to 1993/94 from hospitalized children in Vienna, Austria and Zagreb, Croatia were analysed for antigenic and genetic variations. Twenty-nine of the 32 isolates investigated belonged to group A and 3 to group B, with the majority of infections caused by subgroup A1 (21 of 29). Restriction endonuclease mapping of PCR products derived from parts of the N and G gene of 18 group A strains identified 3 distinct lineages, very similar to those defined by analysis of recurrent epidemics in Birmingham, United Kingdom during the same period. Results of this study provide further information on the global pattern of RSV and show that very similar viruses are present simultaneously in widely separated areas.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Variación Genética / Variación Antigénica / Virus Sincitial Respiratorio Humano / Infecciones por Virus Sincitial Respiratorio Límite: Child / Humans País/Región como asunto: Europa Idioma: En Revista: Arch Virol Año: 1998 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Austria
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Variación Genética / Variación Antigénica / Virus Sincitial Respiratorio Humano / Infecciones por Virus Sincitial Respiratorio Límite: Child / Humans País/Región como asunto: Europa Idioma: En Revista: Arch Virol Año: 1998 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Austria