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Optimizing the delivery of HIV counseling and testing services: the Uganda experience using rapid HIV antibody test algorithms.
Downing, R G; Otten, R A; Marum, E; Biryahwaho, B; Alwano-Edyegu, M G; Sempala, S D; Fridlund, C A; Dondero, T J; Campbell, C; Rayfield, M A.
Afiliación
  • Downing RG; Centers for Disease Control and Prevention/Uganda Virus Research Institute Research Collaboration, Entebbe. cdcrgd@imul.com
Article en En | MEDLINE | ID: mdl-9704945
ABSTRACT
PIP: An evaluation conducted at the AIDS Information Center in Kampala, Uganda, demonstrated that same-day HIV results can be provided in counseling and testing centers without compromising service quality. The Center was established in 1990 in response to widespread public interest in HIV serodiagnosis. By 1996, more than 300,000 clients had been tested. However, 25% of these clients never received their result because of failure to report back to the Center after 2 weeks (the time required for results to be returned from an off-site laboratory) or late arrival of results. To address this problem, the Center evaluated three rapid HIV assays (Sero-Strip, SeroCard, and Capillus) against a standard criterion to identify a testing algorithm that could be used as an on-site confirmatory testing strategy. 325 clients were enrolled in the 5-day evaluation. Individually, all three rapid tests performed well when compared with the standard criterion result. The resulting algorithm (a combination of Capillus as the screening assay and SeroCard as a supplementary assay for initially positive specimens and Multispot as a tie-breaker assay) gave no indeterminate results, was 100% sensitive and specific, and could be integrated easily into existing counseling protocols. The entire process (registration, test decision counseling, phlebotomy, laboratory testing, prevention counseling, and post-test counseling) took an average of 2 hours to complete.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algoritmos / Anticuerpos Anti-VIH / Infecciones por VIH / Consejo / Servicios de Diagnóstico Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: J Acquir Immune Defic Syndr Hum Retrovirol Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) / VIROLOGIA Año: 1998 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algoritmos / Anticuerpos Anti-VIH / Infecciones por VIH / Consejo / Servicios de Diagnóstico Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: J Acquir Immune Defic Syndr Hum Retrovirol Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) / VIROLOGIA Año: 1998 Tipo del documento: Article Pais de publicación: Estados Unidos