Mediator substances of the pineal neuronal network of mammals.
Neurobiology (Bp)
; 5(4): 459-67, 1997.
Article
en En
| MEDLINE
| ID: mdl-9591281
In addition to receptor-type pinealocytes, the mammalian pineal organ contains small and large neurons and ependymal/glial cells as well. Axons of pinealocytes form synaptic ribbon-containing axo-dendritic synapses on large secondary pineal neurons and/or terminate as neurohormonal endings on the basal lamina of the vascular surface of the organ. The small pineal neurons were found to be gamma-aminobutyric acid (GABA)-immunoreactive, while large secondary neurons and pinealocytes contained immunoreactive amino acids (glutamate and aspartate). Glutamate accumulated presynaptically in pinealocytic axon terminals on large secondary neurons and in the axons of these neurons. Glutamate immunoreactive axons of pineal neurons were traced via the pineal tract to the habenular nucleus. Axons containing granular vesicles and coming from extrapineal perikarya are glutamate immunoreactive as well. Aspartate and GABA are also present in some of the myelinated axons, supposedly pinealopetal in the pineal tract.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Glándula Pineal
/
Ácido Aspártico
/
Ácido Glutámico
/
Ácido gamma-Aminobutírico
/
Red Nerviosa
/
Neuronas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Neurobiology (Bp)
Asunto de la revista:
NEUROLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Hungria
Pais de publicación:
Hungria