Bilateral renal cortical necrosis associated with cefuroxime axetil.
Clin Nephrol
; 49(4): 268-70, 1998 Apr.
Article
en En
| MEDLINE
| ID: mdl-9582561
Cefuroxime axetil has been associated with few reported adverse effects. We report a case of bilateral renal cortical necrosis in a female after receiving 7 doses over 4 treatment days. The patient presented with worsening symptoms consisting of arthralgias, pruritus, and abdominal pain. Laboratory data obtained was indicative of worsening renal failure and thrombocytopenia. The patient required hemodialysis by the third day. Kidney biopsy revealed cortical necrosis. The possible pathogenesis of cefuroxime axetil causing cortical necrosis in this case and a review of other reported cases of chemical induced renal cortical necrosis is discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bronquiolitis
/
Cefuroxima
/
Cefalosporinas
/
Necrosis de la Corteza Renal
/
Fallo Renal Crónico
Tipo de estudio:
Risk_factors_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Clin Nephrol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Alemania