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Perceived health modifies the effect of biomedical risk factors in the prediction of acute myocardial infarction. An incident case-control study from northern Sweden.
Weinehall, L; Johnson, O; Jansson, J H; Boman, K; Huhtasaari, F; Hallmans, G; Dahlen, G H; Wall, S.
Afiliación
  • Weinehall L; Department of Epidemiology and Public Health, Umeå University, Sweden. lars.weinehall@epiph.umu.se
J Intern Med ; 243(2): 99-107, 1998 Feb.
Article en En | MEDLINE | ID: mdl-9566637
OBJECTIVES: To assess the importance of biomedical risk factors, social factors and self-reported health in the prediction of the first event of acute myocardial infarction (AMI) in an apparently healthy middle-aged population. DESIGN: An incident case-control study. SETTING: The study was nested within the Västerbotten Intervention Program and the Northern Sweden MONICA cohorts. SUBJECTS: The study consists of 78 AMI cases with two randomly selected controls per case from the same study cohorts. RESULTS: Significant odds ratios were found for history of diabetes, daily smoking, cholesterol, body-mass index, hypertension, lower education and perceived ill health. In multivariate logistic regression smoking, hypertension and cholesterol of > or =7.8 mmol L(-1) remained significant. An interaction was observed between number of biomedical risk factors and perceived health. CONCLUSIONS: Smoking, hypertension and hypercholesterolaemia explain a major share of incident AMI events in a Swedish middle-aged population. The study further illustrates that perceived ill health negatively modifies the impact of these risk factors.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estado de Salud / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude / Patient_preference Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Intern Med Asunto de la revista: MEDICINA INTERNA Año: 1998 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estado de Salud / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude / Patient_preference Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Intern Med Asunto de la revista: MEDICINA INTERNA Año: 1998 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido