[Characterization of 100 patients with tuberculosis treated in the Academic Medical Center in Amsterdam]. / Karakterisering van 100 patiënten met tuberculose behandeld in het Academisch Medisch Centrum te Amsterdam.
Ned Tijdschr Geneeskd
; 142(4): 180-4, 1998 Jan 24.
Article
en Nl
| MEDLINE
| ID: mdl-9557023
OBJECTIVE: To inventory both clinical and demographical data of patients with tuberculosis in the AMC, as well as diagnostic procedures, response to therapy and rate of resistance. DESIGN: Retrospective, descriptive. SETTING: The Academic Medical Center. Amsterdam, the Netherlands. METHOD: The medical records of all patients with a bacteriologically confirmed infection with Mycobacterium tuberculosis complex between January 1993 and December 1995 were studied. RESULTS: 70 out of 100 patients with tuberculosis were not born in the Netherlands. Out of 50 patients tested 18 were HIV positive. The most common abnormality seen on X-rays of non-HIV positive patients were caverns. The X-ray of HIV positive patients showed no abnormalities in 39%; there was no correlation with CD4 cell count. In 74% of the patients with pulmonary tuberculosis the diagnosis was made by culture of the sputum. Treatment consisted of INH, rifampicin, pyrazinamide and ethambutol. Twelve patients were infected with resistant strains, of which two were multidrug resistant. Four patients died of tuberculosis. CONCLUSION: Tuberculosis was seen mostly among immigrants. Only half the patients with tuberculosis were tested for presence of HIV antibodies. Culture and staining of sputum played a key role in the diagnosis of tuberculosis. Multiresistant tuberculosis was present in 2% of the patients. Death due to tuberculosis in this population was 4%.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tuberculosis Pulmonar
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Año:
1998
Tipo del documento:
Article
Pais de publicación:
Países Bajos