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Cerebrospinal fluid levels of alpha-tocopherol (vitamin E) in Parkinson's disease.
Molina, J A; de Bustos, F; Jiménez-Jiménez, F J; Benito-León, J; Ortí-Pareja, M; Gasalla, T; Tallón-Barranco, A; Navarro, J A; Arenas, J; Enríquez-de-Salamanca, R.
Afiliación
  • Molina JA; Department of Neurology, Hospital Universitario Doce de Octubre, Alcala de Henares, Spain.
J Neural Transm (Vienna) ; 104(11-12): 1287-93, 1997.
Article en En | MEDLINE | ID: mdl-9503274
We compared CSF and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 34 patients with Parkinson's disease (PD) and 47 controls. CSF and serum vitamin E levels were correlate. The mean CSF and serum vitamin E levels, and the CSF/serum ratio of PD patients did not differ significantly between the groups. There was no influence of antiparkinsonian therapy on CSF vitamin E levels. CSF vitamin E levels did not correlate with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale of the Hoehn and Yahr staging in the PD group. These results suggest that CSF vitamin E concentrations are unrelated with the risk for PD.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Vitamina E Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neural Transm (Vienna) Año: 1997 Tipo del documento: Article País de afiliación: España Pais de publicación: Austria
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Vitamina E Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neural Transm (Vienna) Año: 1997 Tipo del documento: Article País de afiliación: España Pais de publicación: Austria