Antibiotic susceptibility of Neisseria gonorrhoeae in Trinidad and Tobago.
West Indian Med J
; 46(4): 107-10, 1997 Dec.
Article
en En
| MEDLINE
| ID: mdl-9494404
ABSTRACT
PIP: Neisseria gonorrhoeae from many areas of the world have developed resistance to a wide variety of antibiotics over the past 2 decades. The incidence of treatment failures with standard doses of penicillin observed in Trinidad and Tobago's sexually transmitted disease (STD) clinics suggests that such resistance also exists in Trinidad. 518 Neisseria gonorrhoeae strains were isolated from 1502 male and female patients attending the 7 STD clinics throughout Trinidad during May-October 1992, and tested to identify their antimicrobial susceptibility. 39 strains were resistant to penicillin, including 27 which were positive for beta-lactamase, indicating infection with penicillinase-producing Neisseria gonorrhoeae (PPNG). 51 strains were resistant to tetracycline, of which 26 exhibited high levels of resistance compatible with tetracycline-resistant Neisseria gonorrhoeae (TRNG). 6 strains showed evidence of having both PPNG and TRNG plasmids, and 5 strains showed chromosomally-mediated resistance to both penicillin and tetracycline. The overall resistance rate to penicillin and tetracycline was 17.7%, and there was resistance to neither spectinomycin, cefuroxime, ceftriaxone, nor norfloxacin. The resistance rates observed in this study are significant enough to warrant the cessation of penicillin and tetracycline use in STD clinics, and the use of newer antimicrobials. Neisseria gonorrhoeae resistance patterns demand ongoing monitoring.
Palabras clave
Americas; Antibiotics; Caribbean; Developing Countries; Diseases; Drugs; Gonorrhea--prevention and control; Infections; Measurement; North America; Obstacles; Organization And Administration; Prevalence; Reproductive Tract Infections; Research Methodology; Research Report; Sexually Transmitted Diseases; Treatment; Trinidad And Tobago
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Resistencia a las Penicilinas
/
Resistencia a la Tetraciclina
/
Neisseria gonorrhoeae
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
Caribe ingles
/
Trinidad y tobago
Idioma:
En
Revista:
West Indian Med J
Año:
1997
Tipo del documento:
Article
Pais de publicación:
Jamaica