Primary endocervical extraosseous Ewing's sarcoma/PNET.
Int J Gynecol Pathol
; 17(1): 83-8, 1998 Jan.
Article
en En
| MEDLINE
| ID: mdl-9475198
A 36-year-old woman presented with intermenstrual spotting and was found to have a cystic mass involving the uterine cervix on a pelvic ultrasound examination. A necrotic and hemorrhagic tumor was excised by hysterectomy and processed for light and electron microscopic investigation and molecular analysis. Microscopic examination revealed a small round cell tumor that immunohistochemical studies (including staining for the highly restricted surface antigen p30/32MIC2) and ultrastructural studies indicated was an extraosseous Ewing's sarcoma (EES)/primitive neuroectodermal tumor (PNET). This diagnosis was established by detection of EWS/ERG fusion transcript through reverse transcription polymerase chain reaction (RT-PCR) with nested primers. Full body computed tomography failed to detect any extrauterine tumor, and the patient is clinically free of disease 18 months after hysterectomy. This case represents the first report of a primary EES/PNET arising in the uterine cervix.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sarcoma de Ewing
/
Factores de Transcripción
/
Transactivadores
/
Tumores Neuroectodérmicos Primitivos
/
Proteínas de Unión al ADN
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Int J Gynecol Pathol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Estados Unidos