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Molecular cloning and gene expression of growth hormone-releasing peptide receptor in rat tissues.
Yokote, R; Sato, M; Matsubara, S; Ohye, H; Niimi, M; Murao, K; Takahara, J.
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  • Yokote R; First Department of Internal Medicine, Kagawa Medical University, Japan.
Peptides ; 19(1): 15-20, 1998.
Article en En | MEDLINE | ID: mdl-9437732
We cloned a fragment of the rat GH-releasing peptide (GHRP) receptor homologue and examined the tissue distribution of GHRP receptor mRNA in rats. Sequence analysis showed that the open reading frame is well conserved between rat and human with 96% identity in a 364-amino acid overlap. By reverse transcription-polymerase chain reaction we detected GHRP receptor mRNAs in the rat brain including the hypothalamus, anterior pituitary, and renal pelvis in twenty-eight tissues tested. Microdissection revealed that GHRP receptor mRNAs were localized predominantly in the arcuate nucleus and ventromedial hypothalamus.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Química Encefálica / Receptores de Hormona Reguladora de Hormona Hipofisaria / Receptores de Neuropéptido Límite: Animals / Humans Idioma: En Revista: Peptides Año: 1998 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Química Encefálica / Receptores de Hormona Reguladora de Hormona Hipofisaria / Receptores de Neuropéptido Límite: Animals / Humans Idioma: En Revista: Peptides Año: 1998 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos