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Longitudinal follow-up of two AIDS patients for active human herpesvirus-6 (HHV-6) infection.
Ablashi, D V; Chatlynne, L G; Whitman, J E.
Afiliación
  • Ablashi DV; Advanced Biotechnologies Inc., Columbia, MD 21046, USA.
In Vivo ; 11(5): 383-6, 1997.
Article en En | MEDLINE | ID: mdl-9427039
Because of the demonstrated presence of Human Herpesvirus-6 (HHV-6) in various tissues and organs of HIV-1 infected AIDS patients, and its implication in the pathogenesis of AIDS, we followed two AIDS patients for active HHV-6 infection for two years. Evidence of active HHV-6 infection was demonstrated by immunovirologic assays in both patients; however, the profile of infection in the two patients varied. One patient showed appearance and disappearance of HHV-6, indicating virus reactivation, whereas the other patient showed chronic or persistent HHV-6 infection. Both patients' peripheral blood mononuclear cells (PBMC) contained HIV-1 when their CD4 cell count was approximately 200 mm3. No active HHV-6 was demonstrated in a healthy donor, who was used as a control for this study.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Inmunodeficiencia Adquirida / Herpesvirus Humano 6 / Infecciones por Herpesviridae Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: In Vivo Asunto de la revista: NEOPLASIAS Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Grecia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Inmunodeficiencia Adquirida / Herpesvirus Humano 6 / Infecciones por Herpesviridae Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: In Vivo Asunto de la revista: NEOPLASIAS Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Grecia