Association of sarcoidosis, low-grade B-lymphoma and epidermoid carcinoma.
Postgrad Med J
; 73(863): 580-2, 1997 Sep.
Article
en En
| MEDLINE
| ID: mdl-9373602
We report on a case of the so-called sarcoidosis-lymphoma syndrome in a 65-years-old man diagnosed as having sarcoidosis and, four years later, neurosarcoidosis. The diagnoses of epidermoid carcinoma of the skin and of stage IV monocytoid, small cell lymphocytic lymphoma were made five and seven years, respectively, after the initial diagnosis of sarcoidosis. It has been suggested that the increased mitotic activity of lymphocytes observed in sarcoidosis, favours their malignant transformation. Hypothetically, sarcoidosis might also influence the development of epidermoid carcinomas by depletion of circulating T4 lymphocytes and decreased resistance to oncogenic viruses that could lead to decreased tumour rejection in the epithelia exposed to carcinogenic stimuli.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sarcoidosis
/
Neoplasias Cutáneas
/
Carcinoma de Células Escamosas
/
Leucemia Linfocítica Crónica de Células B
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Postgrad Med J
Año:
1997
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Reino Unido