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Management of acute renal failure in the pediatric patient: hemofiltration versus hemodialysis.
Maxvold, N J; Smoyer, W E; Gardner, J J; Bunchman, T E.
Afiliación
  • Maxvold NJ; University of Michigan Medical Center, Mott Children's Hospital, Ann Arbor 48109, USA.
Am J Kidney Dis ; 30(5 Suppl 4): S84-8, 1997 Nov.
Article en En | MEDLINE | ID: mdl-9372984
Although outcome data for acute renal failure (ARF) in the adult population (analyzed by etiology of ARF, severity of illness, and modality of treatment) are readily available, few similar data exist for the pediatric population. Pediatric survival rate data vary widely, based upon era of analysis, age and size of child, and cause of ARF. Few comparative data are available that address impact by modality chosen to treat ARF. Comparison of 122 children who were treated by hemodialysis (HD; n = 58) versus hemofiltration (HF; n = 64) reveals a combined survival rate of 65%. Survival by modality was higher for HD (83%) than for HF (48%). The major diagnosis treated with HF was sepsis (29/64; 45%), with a survival rate of 31%, whereas the major diagnosis treated with HD (27/58; 46%) was primary renal failure, with a survival rate of 96%. Seventy-one percent of children undergoing HF required pressor support for hypotension, whereas only 24% of those receiving HD needed pressor support (P < 0.01). We conclude that the choice of renal replacement therapy (RRT) modality needs to be determined by the best treatment available. To adequately evaluate therapy measures, further analyses of outcome need to consider those factors that determine choice of RRT and those that affect survival independent of ARF.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diálisis Renal / Hemofiltración / Lesión Renal Aguda Límite: Adolescent / Adult / Child / Child, preschool / Humans / Infant Idioma: En Revista: Am J Kidney Dis Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diálisis Renal / Hemofiltración / Lesión Renal Aguda Límite: Adolescent / Adult / Child / Child, preschool / Humans / Infant Idioma: En Revista: Am J Kidney Dis Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos