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Helicobacter pylori in recently-diagnosed versus chronic duodenal ulcer.
Pest, P; Zárate, J; Varsky, C; Man, F; Schraier, M.
Afiliación
  • Pest P; Servicio de Gastroenterología, Hospital Nacional Posadas, Haedo, Pcia. de Bs. As., Argentina.
Acta Gastroenterol Latinoam ; 26(5): 273-6, 1996.
Article en En | MEDLINE | ID: mdl-9363263
Helicobacter pylori is one of the main causes of type B gastritis and is frequently found in the gastric antrum or in areas of gastric metaplasia in duodenal ulcer patients. The aim of this study was to evaluate Helicobacter pylori and gastric metaplasia prevalence in duodenal ulcer patients within their first diagnosed episode compared to those with chronic ulcer disease. Eighty three patients were prospectively studied in a 2-year period, they were divided into 3 groups: Group I, control, included 29 patients; Group II, 17 patients, included patients with first diagnosed duodenal ulcer episode; and Group III, 37 patients, with chronic ulcer disease. Helicobacter pylori prevalence in duodenum was significatively lower in Group II versus Group III and controls (67.5%, 0% and 3.2% respectively) (p < 0.001). In the antrum Hp prevalence was also lower in Group II compared to Group III and I (41%, 78.3% and 24.1%) with a significative difference (p < 0.001). Gastric metaplasia was significantly higher in Group III versus Group II and controls. These results suggest that Helicobacter pylori plays an important but not exclusive role in the pathogenesis of these disease together with other factors.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Úlcera Duodenal Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Gastroenterol Latinoam Año: 1996 Tipo del documento: Article País de afiliación: Argentina Pais de publicación: Argentina
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Úlcera Duodenal Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Gastroenterol Latinoam Año: 1996 Tipo del documento: Article País de afiliación: Argentina Pais de publicación: Argentina