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Prevalence and risk factors for HTLV-II infection in 913 injecting drug users in Stockholm, 1994.
Krook, A; Albert, J; Andersson, S; Biberfeld, G; Blomberg, J; Eklund, I; Engström, A; Julander, I; Käll, K; Martin, C; Stendahl, P; Struve, J; Sönnerborg, A.
Afiliación
  • Krook A; Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.
J Acquir Immune Defic Syndr Hum Retrovirol ; 15(5): 381-6, 1997 Aug 15.
Article en En | MEDLINE | ID: mdl-9342259
The prevalence and risk factors for acquisition of human T-cell lymphotropic virus type I and II (HTLV-I and II) were investigated in a prospective study of 913 injecting drug users (IDUs) in Stockholm in 1994. Epidemiologic data were recorded, and blood samples were tested for antibodies against HTLV-I and HTLV-II; human immunodeficiency virus (HIV) types 1 and 2; and hepatitis A (HAV), B (HBV), C (HCV), and D (HDV). Positive serologic results for HTLV were confirmed by Western blot (WB) and polymerase chain reaction (PCR). Of the 905 participants with conclusive HTLV-II status, 29 (3.2%) were HTLV-II positive, and all but three were of Nordic descent. None was HTLV-I infected. One person was infected as early as 1981, before HIV had reached the IDU population in Sweden. The prevalence of HTLV-II infection was 12% among HIV-1-seropositive and 1.8% among HIV-1-seronegative participants. The overall seroprevalences were 14% for HIV-1, 0% for HIV-2, 41% for HAV, 75% for HBV, 92% for HCV, and 8% for HDV. Although amphetamine has been the main injecting drug in Sweden for several decades, heroin abuse combined with a debut of injecting drugs before 1975 was identified as the most important risk factor associated with HTLV-II infection. HAV and HIV seropositivity were also independent risk factors.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por HTLV-II / Abuso de Sustancias por Vía Intravenosa Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: J Acquir Immune Defic Syndr Hum Retrovirol Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) / VIROLOGIA Año: 1997 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por HTLV-II / Abuso de Sustancias por Vía Intravenosa Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: J Acquir Immune Defic Syndr Hum Retrovirol Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) / VIROLOGIA Año: 1997 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos