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Diagnosis of lipogranulomatosis (Farber disease) by use of cultured fibroblasts.
J Pediatr ; 89(1): 59-61, 1976 Jul.
Article en En | MEDLINE | ID: mdl-932904
The enzyme defect in Farber disease, a deficiency of acid ceramidase, has been demonstrated in cultured skin fibroblasts, which provides a means of confirming the diagnosis during life. The assay can also be performed using cultured amniotic fluid cells and is a potential tool for detection of carriers of the disease.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ceramidas / Fibroblastos / Amidohidrolasas / Granuloma / Lipidosis Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Pediatr Año: 1976 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ceramidas / Fibroblastos / Amidohidrolasas / Granuloma / Lipidosis Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Pediatr Año: 1976 Tipo del documento: Article Pais de publicación: Estados Unidos