Aging attenuates diurnal variation in hamster locomotion, anxiolysis and GABA turnover.
Neurosci Lett
; 233(1): 9-12, 1997 Sep 12.
Article
en En
| MEDLINE
| ID: mdl-9324227
A decrease in amplitude of wheel running circadian rhythms was found in old (18 month old) Syrian hamsters, as compared with young (3 month old.) animals. In a plus-maze paradigm, amplitude of variation of anxiety-related variables (2400 vs. 1600 h) was significantly impaired in aged hamsters. Cerebral cortex, hypothalamic and pineal gamma-aminobutyric acid (GABA) turnover was higher at night, amplitude of variation being significantly smaller in aged hamsters. The results further support the existence of impaired amplitude of circadian rhythms in aged Syrian hamsters.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ansiedad
/
Envejecimiento
/
Ritmo Circadiano
/
Ácido gamma-Aminobutírico
/
Locomoción
Límite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Año:
1997
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Irlanda