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[Accelerated desensitization for hymenoptera venom allergy in 30 hours: efficacy and safety in 150 cases]. / Désensibilisation accélérée au venin d'hyménoptères en 30 heures: efficacité et sécurité sur 150 cas.
van der Brempt, X; Ledent, C; Mairesse, M.
Afiliación
  • van der Brempt X; Département de Pneumo-allergologie, Clinique Saint-Luc, Bouge.
Rev Med Brux ; 18(3): 120-4, 1997 Jun.
Article en Fr | MEDLINE | ID: mdl-9273600
In this study, we performed 150 desensitizations in 139 Hymenoptera venom allergic patients (109 Yellow jacket allergic patients, 19 Honey bee allergic patients and 11 patients sensitized to both insects, who received a dual desensitization). We used a rush protocol, allowing injection of a total cumulated dose of 125,1 (Honey bee) to 175,1 (Yellow jacket) microgram of venom in 30 hours. Patients were hospitalized, with all emergency precautions for treating systemic reactions. The protocol was well tolerated in 147/150 cases; 3 patients had a benign systemic reaction. Patients received monthly maintenance doses of 100 micrograms venom. 39 patients experienced a field sting during immunotherapy; 2 of them (5%) had a benign systemic reaction. Thus, our rush desensitization protocol seems to be safe and effective.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Avispas / Abejas / Desensibilización Inmunológica / Hipersensibilidad Inmediata / Mordeduras y Picaduras de Insectos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Animals / Child / Child, preschool / Humans / Middle aged Idioma: Fr Revista: Rev Med Brux Año: 1997 Tipo del documento: Article Pais de publicación: Bélgica
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Avispas / Abejas / Desensibilización Inmunológica / Hipersensibilidad Inmediata / Mordeduras y Picaduras de Insectos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Animals / Child / Child, preschool / Humans / Middle aged Idioma: Fr Revista: Rev Med Brux Año: 1997 Tipo del documento: Article Pais de publicación: Bélgica