Pneumothorax as a first manifestation of sarcoidosis.

Froudarakis, M E; Bouros, D; Voloudaki, A; Papiris, S; Kottakis, Y; Constantopoulos, S H; Siafakas, N M

Froudarakis, M E; Bouros, D; Voloudaki, A; Papiris, S; Kottakis, Y; Constantopoulos, S H; Siafakas, N M.

Afiliación

Froudarakis ME; Department of Thoracic Medicine, Medical School, University of Crete, Greece. frudarak@edu.uch.gr

Chest ; 112(1): 278-80, 1997 Jul.

Article en En | MEDLINE | ID: mdl-9228392

RESUMEN

Pneumothorax is a rare manifestation of sarcoidosis, occurring usually late in the course of the disease. We report five cases of pneumothorax as a presenting manifestation of sarcoidosis. In two patients, thoracotomy showed extensive pleural infiltration by noncaseating granulomas. High-resolution CT scans showed cavitated subpleural nodules and subpleural bullae in one case. These findings support that necrosis of subpleural granulomas or rupture of a subpleural bullae, or both, are the mechanisms of pneumothorax in sarcoidosis. Three patients with a lung function impairment were treated with oral corticosteroids. One nontreated patient died due to progression of the disease.

Asunto(s)

Neumotórax/etiología; Sarcoidosis Pulmonar/complicaciones; Adulto; Femenino; Estudios de Seguimiento; Humanos; Masculino; Persona de Mediana Edad; Neumotórax/diagnóstico por imagen; Sarcoidosis Pulmonar/diagnóstico por imagen; Factores de Tiempo; Tomografía Computarizada por Rayos X

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumotórax / Sarcoidosis Pulmonar Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Chest Año: 1997 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos

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