A novel assay for hepatitis B e markers.

Boxall, E H; Peterson, S; Diment, J; Graham, S E; Shirley, J A

Boxall, E H; Peterson, S; Diment, J; Graham, S E; Shirley, J A.

Afiliación

Boxall EH; Birmingham Public Health Laboratory, Birmingham Heartlands Hospital, England.

J Med Virol ; 52(3): 280-5, 1997 Jul.

Article en En | MEDLINE | ID: mdl-9210037

RESUMEN

The evaluation of a novel assay that allows simultaneous testing for hepatitis B e antigen and its antibody in a single well is described. The results of routine application and sequential studies on patients with acute hepatitis B and chronic hepatitis B treated with interferon are presented. The specificity and sensitivity of the assay and its ability to be used to follow the response of a patient during the whole seroconversion episode has been evaluated. The assay proved to give useful information about the reactivity of the sample, especially in those patients who were changing their "e" status.

Asunto(s)

Anticuerpos contra la Hepatitis B/sangre; Antígenos e de la Hepatitis B/sangre; Hepatitis B/inmunología; Inmunoensayo/métodos; Biomarcadores; Estudios de Evaluación como Asunto; Hepatitis B/sangre; Hepatitis B/terapia; Anticuerpos contra la Hepatitis B/inmunología; Antígenos e de la Hepatitis B/inmunología; Humanos; Interferones/uso terapéutico; Juego de Reactivos para Diagnóstico; Reproducibilidad de los Resultados; Sensibilidad y Especificidad

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoensayo / Hepatitis B / Anticuerpos contra la Hepatitis B / Antígenos e de la Hepatitis B Tipo de estudio: Diagnostic_studies / Evaluation_studies Límite: Humans Idioma: En Revista: J Med Virol Año: 1997 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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