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Acetylcholine: oscillation of levels in mouse brain following electroshock.
Stavinoha, W B; Sawa, A; Frazer, J; Weintraub, S T.
Afiliación
  • Stavinoha WB; Department of Pharmacology, University of Texas Health Science Center at San Antanio 78284-7764, USA.
Brain Res Bull ; 43(1): 47-52, 1997.
Article en En | MEDLINE | ID: mdl-9205794
The acetylcholine contents of mouse brain regions were measured in order to investigate the response of cholinergic neurons to electroshock. In this study, mice were subjected to electroshock and then sacrificed by microwave irradiation at time intervals of from 0.4 to 6.9 a after electroshock. In all of the brain regions studied, the acetylcholine concentration appeared to oscillate with a mean period of approximately 2.5 a following electroshock. The rate of recovery of acetylcholine after electroshock was calculated for each brain region from the oscillatory equation obtained by nonlinear regression analysis of the experimental data. The rates of synthesis of acetylcholine derived from these in vivo measurements were substantially higher than have been indicated by other methods.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Acetilcolina / Neuronas Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Brain Res Bull Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Acetilcolina / Neuronas Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Brain Res Bull Año: 1997 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos