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A preliminary report on the use of relon mesh in the repair of eventrations with large parietal defects. An experimental study in rats.
Birbilis, T; Theodoropoulou, E; Birbili, A; Dimas, S; Leutsakos, V.
Afiliación
  • Birbilis T; Department of General Surgery, Polikliniki Athinon General Hospital, Athens, Greece.
J Int Med Res ; 25(3): 135-40, 1997.
Article en En | MEDLINE | ID: mdl-9178145
This experimental study in rats was designed to investigate the tolerability and the mode of healing when commercial relon mesh is used in the repair of large abdominal-wall defects. A defect was created to simulate anatomical derangement of the abdominal wall and a surgical correction was performed using relon mesh. The mesh was implanted intraperitoneally in 18 Wistar albino rats. The animals were killed under anaesthesia 4, 6, 8, 12, 15 or 30 days later and the intra-abdominal viscera were examined macroscopically for adhesions and other evidence of inflammatory reactions. Skin healing usually occurred within 7-8 days of surgery. Microscopic studies were used to confirm the gross findings and showed that maturation of granulation tissue, fibrocyte invasion with encapsulation of the mesh and the appearance of newly formed vessels occurred 2 weeks after surgery. Within 4 weeks a strong layer of connective tissue was present. The relon mesh was tolerated well. These results indicate that the use of relon mesh may provide a cheap alternative means of repairing large abdominal-wall defects.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mallas Quirúrgicas / Cicatrización de Heridas / Trasplante de Piel / Músculos Abdominales Límite: Animals Idioma: En Revista: J Int Med Res Año: 1997 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mallas Quirúrgicas / Cicatrización de Heridas / Trasplante de Piel / Músculos Abdominales Límite: Animals Idioma: En Revista: J Int Med Res Año: 1997 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido