[Erythropoietin in hepatocellular carcinoma]. / L'érythropoïétine dans le carcinome hépatocellulaire.
Bull Cancer
; 83(12): 977-80, 1996 Dec.
Article
en Fr
| MEDLINE
| ID: mdl-9116377
Hemopoietic alterations may occur during tumoral diseases, determining anemia. In most cases, serum EPO levels were lower than normal values. Hepatocellular carcinoma (HCC), one of the most frequent malignancies world-wide, is often characterized by mild anemia and increased serum EPO levels. We studied 30 HCC patients and 20 healthy subjects. We found that HCC patients presented higher serum EPO levels than healthy controls. In HCC patients, there was a significant inverse correlation between serum EPO levels and red blood cell count or hemoglobin levels. We postulated that the elevated serum EPO levels observed in these patients may be due to reduced hepatic clearance of EPO, and to the influence of cytokine-mediated inflammatory factors.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Eritropoyetina
/
Carcinoma Hepatocelular
/
Neoplasias Hepáticas
Tipo de estudio:
Etiology_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Bull Cancer
Año:
1996
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Francia