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Effect of mild cold exposure on whole-body and net hindquarters glucose metabolism in sheep.
Sano, H; Fujita, T; Okoshi, Y; Sasaki, M; Tsushida, M; Hara, S; Tomizawa, N; Ambo, K.
Afiliación
  • Sano H; Department of Bioscience and Technology, Iwate University, Morioka, Japan.
Article en En | MEDLINE | ID: mdl-9080666
Isotope dilution using [U-13C]glucose was combined with measurement of hindquarters arteriovenous difference and blood flow to examine the effect of mild cold exposure on whole-body and net hindquarters glucose metabolism in sheep. Determinations were carried out in a thermoneutral environment (20 +/- 1 degrees C) and on day 5 of mild cold exposure (4 +/- 1 degrees C). Whole-body blood glucose turnover rate was 1.56 and 1.91 mg kg-1 min-1 in the thermoneutral environment and during mild cold exposure, respectively. Net hindquarters glucose uptake was 0.79 and 1.19 mg kg-1 min-1, corresponding to 50 and 61% of whole-body turnover rate, respectively. These results suggest that in sheep the contribution of glucose uptake by the hindquarters tended to increase during mild cold exposure, even though whole-body blood glucose turnover rate did not increase significantly.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Temperatura Corporal / Regulación de la Temperatura Corporal / Frío / Glucosa Límite: Animals Idioma: En Revista: Comp Biochem Physiol B Biochem Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 1997 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Temperatura Corporal / Regulación de la Temperatura Corporal / Frío / Glucosa Límite: Animals Idioma: En Revista: Comp Biochem Physiol B Biochem Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 1997 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido