Streptococcus pneumoniae produces a second haemolysin that is distinct from pneumolysin.

Canvin, J R; Paton, J C; Boulnois, G J; Andrew, P W; Mitchell, T J

Canvin, J R; Paton, J C; Boulnois, G J; Andrew, P W; Mitchell, T J.

Afiliación

Canvin JR; Department of Microbiology and Immunology, University of Leicester, U.K.

Microb Pathog ; 22(3): 129-32, 1997 Mar.

Article en En | MEDLINE | ID: mdl-9075215

RESUMEN

Pneumococci are described as alpha-haemolytic but under certain circumstances they produce zones of beta-haemolysis on blood-containing medium. This observation was investigated using wild type strains and a genetically-modified strain unable to produce the haemolytic toxin, pneumolysin. beta-haemolysis was produced by all pneumococci tested. It was not inhibited by anti-pneumolysin antibody but could be inactivated by cholesterol. These data confirm that pneumococci elaborate a second haemolysin, distinct from pneumolysin.

Asunto(s)

Proteínas Hemolisinas/metabolismo; Streptococcus pneumoniae/metabolismo; Anticuerpos Antibacterianos/inmunología; Proteínas Bacterianas; Colesterol/farmacología; Escherichia coli/genética; Proteínas Hemolisinas/efectos de los fármacos; Proteínas Hemolisinas/inmunología; Hemólisis/efectos de los fármacos; Hemólisis/genética; Hemólisis/inmunología; Streptococcus/metabolismo; Streptococcus pneumoniae/genética; Estreptolisinas/genética; Estreptolisinas/inmunología; Estreptolisinas/metabolismo

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Streptococcus pneumoniae / Proteínas Hemolisinas Idioma: En Revista: Microb Pathog Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 1997 Tipo del documento: Article Pais de publicación: Reino Unido

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