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Liver inflammation and acute respiratory distress syndrome in a patient receiving hepatitis B vaccine: a possible relationship?
Ranieri, V M; Dell'Erba, A; Gentile, A; Bruno, F; La Gioia, V; Spagnolo, A; Sacco, R; Caruso, G; Antonaci, S; Schiraldi, O; Brienza, A.
Afiliación
  • Ranieri VM; Istituto di Medicina Legale, Università di Bari, Ospedale Policlinico, Italy.
Intensive Care Med ; 23(1): 119-21, 1997 Jan.
Article en En | MEDLINE | ID: mdl-9037652
We describe a patient in whom clinical evidence of liver and lung dysfunction developed after he received the second dose of recombinant hepatitis B vaccine, despite no serologic evidence of viral hepatitis. However, liver biopsy specimens demonstrated both surface antigens and core antigens, possibly indicating silent hepatitis B virus infection. A search for an infective etiology for the patient's subsequent clinical deterioration in lung function did not yield pathogens: postmortem examination revealed evidence of immune complex-mediated organ injury in the liver, lungs, and kidneys.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Vacunas contra Hepatitis B / Enfermedad Hepática Inducida por Sustancias y Drogas / Hígado Límite: Humans / Male / Middle aged Idioma: En Revista: Intensive Care Med Año: 1997 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Vacunas contra Hepatitis B / Enfermedad Hepática Inducida por Sustancias y Drogas / Hígado Límite: Humans / Male / Middle aged Idioma: En Revista: Intensive Care Med Año: 1997 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos