The alpha/beta fold family of proteins database and the cholinesterase gene server ESTHER.
Nucleic Acids Res
; 25(1): 143-6, 1997 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-9016525
ESTHER (for esterases, alpha/betahydrolase enzyme and relatives) is a database of sequences phylogenetically related to cholinesterases. These sequences define a homogeneous group of enzymes (carboxylesterases, lipases and hormone-sensitive lipases) sharing a similar structure of a central beta-sheet surrounded by alpha-helices. Among these proteins a wide range of functions can be found (hydrolases, adhesion molecules, hormone precursors). The purpose of ESTHER is to help comparison of structures and functions of members of the family. Since the last release, new features have been added to the server. A BLAST comparison tool allows sequence homology searches within the database sequences. New sections are available: kinetics and inhibitors of cholinesterases, fasciculin-acetylcholinesterase interaction and a gene structure review. The mutation analysis compilation has been improved with three-dimensional images. A mailing list has been created.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Colinesterasas
/
Bases de Datos Factuales
/
Lipasa
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nucleic Acids Res
Año:
1997
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Reino Unido