[Abnormalitis in the distributions of ventilation-perfusion ratios and diffusing capacity-perfusion ratios in three types of chronic obstructive pulmonary disease].
Nihon Kyobu Shikkan Gakkai Zasshi
; 34(8): 856-63, 1996 Aug.
Article
en Ja
| MEDLINE
| ID: mdl-8965394
To assess whether diffusion-limited gas exchange plays a significant role in hypoxemia in various types of chronic obstructive pulmonary disease(COPD), we analyzed the distribution of ventilation-perfusion (VA/Q) ratios and of diffusing capacity-perfusion (G/Q) ratios. We compared VA/Q and G/Q distribution in patients with three basic types of COPD: emphysematous changes, bronchiolar involvement, and airway hypersecretion, which were classified based on symptoms and on findings of high-resolution CT. The results were that 1) hypoxemia was not caused by diffusion-limited gas exchange with low G/Q regions in any type of COPD, that 2) hypoxemia was not caused by inhomogeneities in VA/Q distribution, that 3) emphysematous changes and bronchiolar involvement were associated with high and low VA/Q regions, respectively, and that 4) either hypersecretion itself or related airway abnormalities may cause low VA/Q regions to form.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Capacidad de Difusión Pulmonar
/
Relación Ventilacion-Perfusión
/
Enfermedades Pulmonares Obstructivas
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Nihon Kyobu Shikkan Gakkai Zasshi
Año:
1996
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Japón