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Orthotopic liver transplantation in two patients with hypertrophic obstructive cardiomyopathy.
Harley, I D; Jones, E F; Liu, G; McCall, P R; McNicol, P L.
Afiliación
  • Harley ID; Department of Anaesthesia and Intensive Care, Austin Hospital, Heidelberg, Victoria, Australia.
Br J Anaesth ; 77(5): 675-7, 1996 Nov.
Article en En | MEDLINE | ID: mdl-8957992
Orthotopic liver transplantation (OLT) in patients with end-stage liver disease is a procedure associated with high cardiac output, low systemic vascular resistance (SVR), coagulopathy and the potential for significant blood loss. A feature of hypertrophic obstructive cardiomyopathy (HOCM) is left ventricular outflow tract obstruction which may be exacerbated by reduced SVR, reduced filling pressures, tachycardia and positive inotropy. We report two cases of OLT in patients with HOCM. Our anaesthetic technique involved the use of halothane and vecuronium and avoidance of drugs causing tachycardia and positive inotropy. Management was aided by intraoperative transoesophageal echocardiography which showed that filling pressures poorly reflected end-diastolic volumes. Volume administration, vasoconstrictors and avoidance of inotropes and chronotropes reduced the outflow tract obstruction which was particularly severe in the reperfusion period.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Monitoreo Intraoperatorio / Trasplante de Hígado / Ecocardiografía Transesofágica / Anestesia General Límite: Humans / Male / Middle aged Idioma: En Revista: Br J Anaesth Año: 1996 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cardiomiopatía Hipertrófica / Monitoreo Intraoperatorio / Trasplante de Hígado / Ecocardiografía Transesofágica / Anestesia General Límite: Humans / Male / Middle aged Idioma: En Revista: Br J Anaesth Año: 1996 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido