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The quest for living-related kidney donors for children with end-stage renal disease.
Etheredge, E E; Zarifian, A; Frentz, G D; Boineau, F G.
Afiliación
  • Etheredge EE; Tulane Regional Transplant Program, Tulane University Medical Center, New Orleans, Louisiana 70112, USA.
Clin Transplant ; 10(4): 352-6, 1996 Aug.
Article en En | MEDLINE | ID: mdl-8884108
In a pediatric renal transplant program that actively seeks living-related kidney donors, we achieved a living donor rate of 55% in 119 children. This approximates the national average but is less than an idealized goal. For black children, the living-donor transplant rate was 41%, a disconcertingly low rate. In an attempt to define factors that negatively affected living-related donor availability, we analyzed our evaluation process by distinct phases (interview, histocompatibility testing and medical evaluation). We classified our families on the basis of locale (urban, suburban and rural), family unit (two or less parents, adult sibs or other relatives presenting at interview) and economic status (designating only economic-disadvantaged and other). While histoincompatibility is predictably a negative factor, the negative impacts of medical illness in the donor pool, economic disadvantage and single parent family are striking and cumulative. Our data validate the relative success of an aggressive recruitment policy in a patient population that includes many economically disadvantaged families. For pediatric renal transplant programs with low living-related donor rates, our data should encourage review and possible modification of the donor recruitment process.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Riñón / Donadores Vivos / Fallo Renal Crónico Tipo de estudio: Prognostic_studies Límite: Adult / Child / Humans País/Región como asunto: America do norte Idioma: En Revista: Clin Transplant Asunto de la revista: TRANSPLANTE Año: 1996 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Dinamarca
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Riñón / Donadores Vivos / Fallo Renal Crónico Tipo de estudio: Prognostic_studies Límite: Adult / Child / Humans País/Región como asunto: America do norte Idioma: En Revista: Clin Transplant Asunto de la revista: TRANSPLANTE Año: 1996 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Dinamarca