Iron decreases the nuclear but not the cytosolic content of the neurohormone melatonin in several tissues in chicks.
J Cell Biochem
; 60(3): 317-21, 1996 Mar 01.
Article
en En
| MEDLINE
| ID: mdl-8867807
This paper describes the influence of iron on both nuclear and cytosolic melatonin contents in several tissues of chicks. The neurohormone melatonin was estimated by means of radioimmunoassay. Iron, administered as FeCl3, decreased the nuclear melatonin level in a variety of tissues, including brain, heart, lung, kidney, and erythrocytes (nucleated cells in chicks) but was not seen in either the liver or gut. All variations related with iron were seen in the nuclear fraction, while only in the pineal gland did the melatonin content of the cytosol change as a result of iron treatment. We also observed a day-night rhythm in the nuclear melatonin: high nuclear levels of melatonin at night and low levels during the light period. This is the first report of nuclear localization of melatonin in any avian cell.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Núcleo Celular
/
Hierro
/
Melatonina
Límite:
Animals
Idioma:
En
Revista:
J Cell Biochem
Año:
1996
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Estados Unidos