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Early experience with the contraceptive use of depot medroxyprogesterone acetate in an inner-city clinic population.
Polaneczky, M; Guarnaccia, M; Alon, J; Wiley, J.
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  • Polaneczky M; Department of Obstetrics and Gynecology, New York Hospital-Cornell Medical College, USA.
Fam Plann Perspect ; 28(4): 174-8, 1996.
Article en En | MEDLINE | ID: mdl-8853283
ABSTRACT
PIP: An exploratory study of 261 US women who initiated use of depot medroxyprogesterone acetate (DMPA) between December 1992 and June 1994 at a hospital- or community-based clinic in New York City highlighted the importance of side effects to method discontinuation. The mean age of DMPA users was 25 years; 70% were unmarried and 84% were Medicaid recipients. At the time of first injection, 58% were using no contraceptive method. At telephone interview, the average time since first injection was 8.6 months. The continuation rate was 81% at 3 months, 63% at 6 months, 52% at 9 months, and 42% at 12 months. When these rates were adjusted to assume that the 37 women who were not locatable for follow-up had discontinued, they became 74%, 53%, 39%, and 30%, respectively. There was no variation in discontinuation rates on the basis of age, parity, marital status, insurance status, number of pregnancies or abortions, postpartum status, or residence. Among the 96 discontinuers for whom data were available, the most frequently cited reasons were abnormal bleeding (30%), weight gain (24%), and nausea (12%). The percentage of women with amenorrhea was 34% at 3 months, 43% at 6 months, 66% at 9 months, and 60% at 12 months. Among adults, the risk of discontinuation was highest in the 3 months after the second injection; in contrast, the risk of discontinuation among adolescents increased steadily during the first year of use. Given the strong association between DMPA side effects and discontinuation, clinic staff are urged to pursue interventions such as estrogen therapy for amenorrhea and nutrition and exercise counseling for weight gain.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetato de Medroxiprogesterona / Anticonceptivos Femeninos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality Límite: Adolescent / Adult / Female / Humans / Pregnancy País/Región como asunto: America do norte Idioma: En Revista: Fam Plann Perspect Año: 1996 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetato de Medroxiprogesterona / Anticonceptivos Femeninos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality Límite: Adolescent / Adult / Female / Humans / Pregnancy País/Región como asunto: America do norte Idioma: En Revista: Fam Plann Perspect Año: 1996 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos