[Wilson-Jones type angiosarcoma with marked response to intrapleural administration of interleukin-2].
Nihon Kyobu Shikkan Gakkai Zasshi
; 33(12): 1441-5, 1995 Dec.
Article
en Ja
| MEDLINE
| ID: mdl-8822000
A 64-year-old woman was admitted to our hospital with a hemothorax after one year of therapy for angiosarcoma that had arisen from the skin of the head. The hemothorax was believed to have resulted from metastasis of the angiosarcoma. Interleukin-2 (IL-2) at a dose of 20 x 10(4) U once daily was administered intrapleurally. Clinical improvement was first observed on the second day after the first dose of IL-2. Increases in natural and in lymphokine-activated killer activity of lymphocytes in pleural effusion were found on the eighth day. Starting on the 16th day of IL-2 therapy, no more fluid was drained, so administration of IL-2 was stopped. The clinical course indicated that the pleural effusion disappeared not because of pleurodesis but because of the anti-cancer effects of IL-2. There were no marked side effects, and intrapleural administration of IL-2 may be useful in patients with hemothorax due to metastasis of angiosarcoma.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Interleucina-2
/
Hemotórax
/
Hemangiosarcoma
/
Neoplasias Pulmonares
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
Ja
Revista:
Nihon Kyobu Shikkan Gakkai Zasshi
Año:
1995
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Japón