[Studies on ethmozine sustained-release tablet remaining-floating in stomach].
Yao Xue Xue Bao
; 31(1): 54-8, 1996.
Article
en Zh
| MEDLINE
| ID: mdl-8762461
An oral sustained-release system of ethmozine (E-HBS) was developed. The in vitro release characteristics of E-HBS were shown primarily to be of the first order of kinetics (Kr = 0.2436 h-1). The gamma-scintiphotographic study showed that E-HBS remained in the human stomach for more than 6 hours after ingestion, much longer than the conventional tablet (1-1.5 h). The plasma concentration-time curve of E-HBS exhibited typical sustained-release characteristics. The percentage of drug released in vitro vs the percentage of drug release in vivo of E-HBS indicated excellent linearity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Moricizina
/
Mucosa Gástrica
Límite:
Adult
/
Humans
/
Male
Idioma:
Zh
Revista:
Yao Xue Xue Bao
Año:
1996
Tipo del documento:
Article
Pais de publicación:
China