Drosophila differentiation genes instrumental in tumor suppression.
Int J Dev Biol
; 40(1): 149-56, 1996 Feb.
Article
en En
| MEDLINE
| ID: mdl-8735924
Tumor suppressor genes of Drosophila are developmental genes which, in the homozygously mutated state, induce in one step malignant or benign neoplastic transformation of specific cell types. They act early in development and by this set the stage for cell specific differentiation of imaginal discs, adult optic neuroblasts, blood and gonial cells. The structure, expression and possible function of the following four tumor suppressor genes are discussed: tumorous imaginal disc, lethal (3) malignant brain tumor, lethal (3) malignant blood neoplasm-1 and benign (2) gonial cell neoplasm.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Genes Supresores de Tumor
/
Genes de Insecto
/
Drosophila
Límite:
Animals
Idioma:
En
Revista:
Int J Dev Biol
Asunto de la revista:
BIOLOGIA
/
EMBRIOLOGIA
Año:
1996
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
España