[pS2 protein and breast cancer].

Torre, E A; Fulco, R A

[pS2 protein and breast cancer]. / Proteina pS2 e carcinoma mammario.

Torre, E A; Fulco, R A.

Afiliación

Torre EA; Istituto Nazionale per la Ricerca sul Cancro, Genova.

Minerva Ginecol ; 47(12): 553-6, 1995 Dec.

Article en It | MEDLINE | ID: mdl-8720977

RESUMEN

pS2 is a small protein (7000 daltons) that is prevalently expressed in human breast cancer positive for estrogen receptors: protein is, in fact, induced by estrogen stimulation. Studies indicate that pS2 protein is a marker for hormone-dependent breast tumors and that its expression is helpful in the prognosis. The presence of pS2, in fact, besides being associated in 96% of the cases to the positivities for estrogen receptors, is associated with longer overall, and disease free, survival. The pS2 protein is also expressed in normal stomach mucosa; its physiological function is unknown.

Asunto(s)

Neoplasias de la Mama/metabolismo; Proteínas de Neoplasias/análisis; Proteínas; Receptores de Estradiol/análisis; Receptores de Estrógenos/análisis; Biomarcadores de Tumor/análisis; Femenino; Humanos; Inmunohistoquímica; Proteínas de Neoplasias/fisiología; Neoplasias Hormono-Dependientes; Pronóstico; Radioinmunoensayo; Receptores de Estradiol/metabolismo; Factor Trefoil-1; Proteínas Supresoras de Tumor

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteínas / Receptores de Estradiol / Receptores de Estrógenos / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: It Revista: Minerva Ginecol Año: 1995 Tipo del documento: Article Pais de publicación: Italia

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links