Protection of kidney cell against ischaemic damage by decreased kidney temperature.
Acta Univ Palacki Olomuc Fac Med
; 138: 55-7, 1994.
Article
en En
| MEDLINE
| ID: mdl-8714096
At normal body temperature, kidney cells are highly sensitive to hypoxia. However, a bloodless operative field is advantageous in some interventions on the kidney. Kidney cells can be protected against the damage that might occur once blood flow has been interrupted pharmacologically or physically by reducing their temperature. The authors compare several methods for achieving renal hypothermia, including a method based on a device they developed themselves to eliminate defects found in existing equipment. The thermal curve obtained when the kidney is immersed in an oil bath cooled to 5 degrees C served as a model for other methods. Using the revised coil developed by the authors, renal hypothermia was achieved safely and efficiently. A combination of pharmacological and physiological methods is preferrable however in order to potentiate the effect of decreased temperature. This method was tested experimentally and then successfully applied in clinical practice.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hipotermia Inducida
/
Isquemia
/
Riñón
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Acta Univ Palacki Olomuc Fac Med
Año:
1994
Tipo del documento:
Article
País de afiliación:
República Checa
Pais de publicación:
República Checa