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Human immunodeficiency virus infection and AIDS in east Africa: challenges and possibilities for prevention and control.
Mhalu, F S; Lyamuya, E.
Afiliación
  • Mhalu FS; Department of Microbiology/Immunology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania.
East Afr Med J ; 73(1): 13-9, 1996 Jan.
Article en En | MEDLINE | ID: mdl-8625855
ABSTRACT
PIP: HIV/AIDS poses a major health and socioeconomic burden in east Africa. More than 50% of adults and 10-15% of children admitted to some of the national and provincial hospitals in the region have HIV/AIDS. AIDS is the leading cause of death among people aged 15-45. Tuberculosis, an opportunistic infection associated with HIV infection, has risen more than three times in some east African countries. 10-30% of adults in urban areas and from less than 1% to 25% of adults in rural areas are infected with HIV. In fact, HIV prevalence is still increasing; so the full impact of AIDS in eastern Africa has not yet occurred. Yet in many developed countries, HIV infection has peaked and HIV/AIDS is no longer a top priority. Poverty, ignorance, high prevalence of other sexually transmitted diseases (STDs), and associated cultural and traditional practices (e.g., inheritance of widows and polygamy), which abound and facilitate HIV transmission, account for the differences in HIV prevalence between east Africa and developed countries. Heterosexual intercourse accounts for more than 80% of HIV infections in east Africa. Perinatal transmission accounts for 5-15% of HIV cases. Blood and blood products transmitted HIV in the remaining cases. There have been considerable scientific advances in immunopathology of AIDS, diagnostics, and social behavioral studies; yet a cure and/or an effective vaccine is not in the near future. Recently, scientists have discovered that a mother's use of zidovudine during the last weeks of pregnancy and labor and zidovudine administered to the newborn significantly reduce perinatal HIV transmission. The knowledge and tools for preventing HIV transmission are available worldwide, but AIDS control in eastern Africa is apt to be for naught unless strong efforts are implemented toward the reduction of poverty, ignorance, and in the control of other common STDs.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Seroprevalencia de VIH / Países en Desarrollo Tipo de estudio: Etiology_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: East Afr Med J Año: 1996 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Kenia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Seroprevalencia de VIH / Países en Desarrollo Tipo de estudio: Etiology_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: East Afr Med J Año: 1996 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Kenia