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"Sunbath polyneuritis": subacute axonal neuropathy in perazine-treated patients after intense sun exposure.
Roelcke, U; Hornstein, C; Hund, E; Schmitt, H P; Siess, R; Kaltenmaier, M; Fassler, J; Meinck, H M.
Afiliación
  • Roelcke U; University Department of Neurology, Heidelberg, Germany.
Muscle Nerve ; 19(4): 438-41, 1996 Apr.
Article en En | MEDLINE | ID: mdl-8622721
This article aims at drawing attention to the peculiar association of intense exposure to sunlight and subacute development of sensory neuropathy which was seen in 7 psychiatric patients treated with the phenothiazine derivative, perazine. Three patients additionally developed bilateral VII nerve palsy. Symptoms followed a monophasic course with almost complete remission. Routine neurophysiology suggested axonal neuropathy confirmed by sural nerve biopsy in 1 patient. A toxic origin of neuropathy is supposed, possibly induced by phenothiazine photoproducts, which may cause cell damage via lipid peroxidation.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perazina / Traumatismos por Radiación / Enfermedades del Sistema Nervioso Periférico / Helioterapia / Neuritis Tipo de estudio: Etiology_studies Límite: Adult / Aged / Female / Humans / Male Idioma: En Revista: Muscle Nerve Año: 1996 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perazina / Traumatismos por Radiación / Enfermedades del Sistema Nervioso Periférico / Helioterapia / Neuritis Tipo de estudio: Etiology_studies Límite: Adult / Aged / Female / Humans / Male Idioma: En Revista: Muscle Nerve Año: 1996 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos