Structure and effects of a kinin potentiating fraction F (AppF) isolated from Agkistrodon piscivorus piscivorus venom.
Toxicon
; 33(10): 1313-9, 1995 Oct.
Article
en En
| MEDLINE
| ID: mdl-8599182
The contractile action of bradykinin on isolated smooth muscles is known to be potentiated by special peptides isolated from snake venoms and other animal sources. A fraction F (AppF) has been derived from Agkistrodon piscivorus piscivorus venom. This fraction does not increase the depressor effect of bradykinin n blood pressure, potentiates the action of bradykinin on isolated guinea-pig ileum and prolongs the duration of relaxation in isolated rat duodenum. This fraction was able to inhibit the conversion of angiotensin I to angiotensin II in vitro. The primary structure of this decapeptide is given.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligopéptidos
/
Fragmentos de Péptidos
/
Presión Sanguínea
/
Venenos de Crotálidos
/
Músculo Liso
Límite:
Animals
Idioma:
En
Revista:
Toxicon
Año:
1995
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Reino Unido